• psycotica0@lemmy.ca
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    10 hours ago

    I’ve been sad lately, watching the creaky old mice shuffling around my yard, so it’s nice that there’s something coming down the pipe to help them regain mobility.

  • ikt@aussie.zone
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    23 hours ago

    man all the shit that works on mice

    we must have made super jacked non-aging bio mice by now

    seriously though hope this transfers, shitty joints just suck, no fun at all - signed an algae oil drinker

    • chaogomu@lemmy.world
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      22 hours ago

      This drug has already gone through Phase 1 human trials for a separate condition.

      Phase 1 trials only test safety in healthy adults, but this drug passed. (Still awaiting the paper on the trial)

      The delivery method was a once a day pill.

    • Danarchy@lemmy.nz
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      18 hours ago

      Some of us already do bro… just the other day I told off a fella “never speak to me or my super jacked non-aging bio mouse again”

    • corsicanguppy@lemmy.ca
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      23 hours ago

      Right? After a lifetime of walking, I’m gonna need some work soon – feet, mainly. Please let this get to an applicable fix before it’s too late!

  • saltesc@lemmy.world
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    21 hours ago

    I think a part of getting older is just watching medical science get better as the world gets shittier and realising the two cancel each other out so a natural death is still the preferred option. This is probably how people felt off the back of a world war, the depression, and then in the middle of another world war, someone’s like,

    “Check out penicillin! I accidentally discovered it like a decade ago.”

    “Nah, I’m good, thanks.”

    • Mycatiskai@lemmy.ca
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      17 hours ago

      Yeah my dad was discussing MAID (medically assisted death) recently, he is in his late 70s.

      He lost his heel in a motorcycle accident in the 1970s and they butchered up his right inner thing taking a chunk out and putting it on his foot. So now both his legs are in constant pain and he spends most of his day high as a kite to deal with the pain. He can barely walk anymore. He got through cancer a few years back which made matters worse and he lost his sense of taste so he gets to be in pain all day and not taste anything enjoyable.

      Nothing medical is going to improve his life drastically so if MAID is what he wants then I will support him.

    • Itsamelemmy@lemmy.zip
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      22 hours ago

      My wife recently had her knee replaced. After seeing her recovery, hopefully this is available before I need mine done. Otherwise, it’s gonna have to hurt like hell non stop before I consider getting mine done.

  • antbricks@lemmy.today
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    22 hours ago

    Semaglutides and other weight loss drugs will hopefully make this treatment less needed in the future. I hope this somehow gets funding, testing, and approval before then to help all the folks with existing damage.

    • elucubra@sopuli.xyz
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      19 hours ago

      weight loss drugs? How about having a fucking decent diet. I mean, the whole “I need drugs to reach a healthy weight because I eat like shit” is really moronic.

      • tetrachromacy@lemmy.world
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        17 hours ago

        This is a privileged viewpoint. Some people have problems losing weight because sugary foods are literally addicting(and in the US at least suffer is added to nearly everything). Some people experience what’s called “food noise”, in which their brain is constantly thinking about eating something, which can be a tremendous ongoing strain to block. Everyone is different, and just because some people can diet without going mad or breaking from the strain doesn’t mean it should be that way for everyone.

        Think about the weight loss drugs being less of an easy way to lose weight and more like it’s addressing the mental and physical aspect of weight loss. If you’ve got food noise and an unhealthy relationship with food, then even if you’re able to master your cravings, it takes an outsize amount of your concentration/spoons to handle. This can leave one deficient in other areas like maintaining their mental health, interpersonal relationships, hygiene, or any number of other things. It’s not a moral or personal failing to need help, dieting or otherwise.

        • elucubra@sopuli.xyz
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          5 hours ago

          I’m a trained addiction recovery meeting facilitator. I’m conversant with addiction and it’s mechanisms. I have recovered from substance mismanagement. I have lost 40 Kg. I’m not a person with superhuman will. No one goes mad by dieting. It may be hard, but I hate to tell you, there is no law in the universe that says that you have a right to an easy life. That’s one of the misconceptions most Americans have.They believe that the constitution grants them the right to be happy. Nope. It grants you the right to pursue happiness.

          Weight loss medication doesn’t address the mental aspect, as you claim, only the physical aspect, and only while being on the drug. It’s a classic pharma dependency strategy.

          The whole thing about fat shaming is misguided. It’s absolutely true that being vicious against people with eating disorders/ignorance is cruel, bad. However this doesn’t mean that people who are obese because of eating habits should be coddled. They should be guided towards healthier approaches to food. The person is not the habit. The person should not be condemned, but the habit should. The fact that in the US health care is essentially reactive facilitates obesity. The concept that resources should be allotted to reactive and dependency ceating medication, as opposed to education and support, is absolutely misguided.

          In my country there is a lot less obesity, partly because the attitude towards food is saner, but also because health care is preventative. I have regular appointments with my registered nurse, who tracks my lifestyle habits, and is the point of contact with the health system.

          • itsAsin@lemmy.world
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            55 minutes ago

            It may be hard, but I hate to tell you, there is no law in the universe that says that you have a right to an easy life.

            there is also no law that says that the right choice should be the difficult one… especially needlessly difficult.

            humans, ALL humans are by nature lazy. and i know for myself from experience that most of the time i will not make the right choice if it involves struggle and sacrifice.

            i am very grateful for the glp1 medications and hope that the medical field can continue to ease the burdens of living a healthy life.

        • halcyoncmdr@piefed.social
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          11 hours ago

          And that doesn’t even begin to touch the subject of food deserts. Many areas of the country, in the middle of dense cities, have absolutely no grocery stores for miles even if people want to be healthy and make food at home.

          • elucubra@sopuli.xyz
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            4 hours ago

            Ok. So the solution to food deserts is medicating people? That’s like saying that the solution to blown tires is more tire repair shops, instead of bettering roads.

      • khannie@lemmy.world
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        17 hours ago

        This is such a short sighted view. Humans are designed to eat more than they need for very good evolutionary reasons, we’re just at the point now where you can do so for pennies. Obesity is on the rise everywhere as a result of this.

        There are factors outside “just eat better bro” at play here. Carbs are incredibly cheap these days and eating healthily is comparatively expensive. There’s a reason (several really) that obesity is higher among lower income folks. You couple that with “food desserts”, ready meals and lack of free time and it’s a terrible recipe.

        I eat well myself and I consider myself lucky to be able to do so. Just a little of putting yourself in the shoes of someone else and not assuming laziness would do you the world of good.

        • elucubra@sopuli.xyz
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          4 hours ago

          yes, overeating in abundance periods, to survive lean times is a defense mechanism. Fat is an energy reserve system, completely natural, but it’s not in modern times, where sugars are so prevalent. What you posit is partly true, but things as simple as eating healthier non fresh foods can be achieved. Eat a can of green beans instead of twinkies. Not ideal, but with proper food education, the food desert problem can be mitigated. Instead of eating Spam, eat frozen chicken, for example. Cheap and heaps healthier.

  • daannii@lemmy.world
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    17 hours ago

    Arthritis causes bone damage too. So. Idk how it’s going to regrow bone joints by repairing cartilage but I’m not a medical doctor.

    I realize bone can repair itself but there are limits.