Yes. If it’s not a AAA multiplayer game, you can basically just assume it works at this point. I don’t bother checking if a game runs now. They always do, unless it’s by EA, Ubisoft, or from China. In fact, I’ve found older games have an easier time than on Windows. WINE handles compatability better than Windows does, and does a better job faking older versions of Windows.

If you need to check, protondb is where you check. Again though, I don’t even bother checking anymore. Everything works.